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VCF files are scanned by this diagnostic tool for known diagnostic disease-associated variants. When no diagnostic mutation is found, the file can be sent to the disease-causing gene discovery tool to see whether new disease associated variants can be found.
@@ -16,4 +15,4 @@ TEAM (27) is an intuitive and easy-to-use web tool that fills the gap between th
@@ -16,4 +15,4 @@ TEAM (27) is an intuitive and easy-to-use web tool that fills the gap between th

**Figure 5.** Interface of the application. Panels for defining targeted regions of interest can be set up by just drag and drop known disease genes or disease definitions from the lists. Thus, virtual panels can be interactively improved as the knowledge of the disease increases.